What causes a U0645 code?

U0645 can be triggered by several issues — see the verified probable causes and step-by-step diagnostics shared by mechanics and owners on OBDIY.

Can I drive with a U0645 code?

Drivability depends on the severity. Check the severity rating and verified driver reports on this page before continuing to drive with U0645 active.

Follow the step-by-step diagnostic on this page, then read the verified fixes contributed by other Heavy Truck owners — the answer marked "Verified Cause" worked for the original poster.

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OBD-II

U0645

Network/CAN bus communication code U0645

What it means

Lost communication with the Turbocharger Control Module. The ECU cannot adjust boost pressure levels.

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